While I’ve never had an injection myself, I’ve heard from others that the process isn’t nearly as daunting as it seems. I’d be interested to hear others’ reactions.
Like other erectile dysfunction remedies, injections work by relaxing the smooth muscles of the penis so that blood vessels dilate and allow strong blood flow into the penis’s erectile tissue. One of the substances used most widely in penile injections is called Trimix, which combines three medications: alprostadil, phentolamine, and papaverine.
Your first few injections are almost always performed by a doctor in his or her office so it can be determined what concentration of Trimix is needed to allow you to achieve an erection. The doctor will also monitor your first couple of self-injections to ensure that you fully understand the procedure. You can read more about penile injection therapy at this site operated by Memorial Sloan Kettering Cancer Center.