Adderall doesn’t directly affect blood flow to the penis. But it can produce an emotional climate that doesn’t mesh well with sexual feelings. A man considering taking Adderall or a similar drug doesn’t need to worry that it will affect the hydraulics of his erections. But he should be aware that emotional effects of the drug can indirectly affect his sex drive, and this can cause a self-reinforcing cycle of problems. It can also lead to relationship problems if not understood properly.