Viagra
Viagrabyedquestions

I know that Viagra is called a PDE5 inhibitor, but I have no idea what that really means. How do drugs of that type work and, more importantly, will Viagra work for me?

Sildenafil citrate, the active ingredient in Cialis, belongs to a family of medications known collectively as PDE5 inhibitors. They are so called because they are able to temporarily sideline an enzyme known as phosphodiesterase-5, which can interfere with blood flow to the penis.

Erections originate in the brain when that organ detects feelings of sexual desire or physical stimuli to the male genitals or other erogenous zones. When the brain receives such signals, it releases a flood of nitric oxide coursing toward the pelvic region, setting off secondary chemical reactions as it goes. One of those reactions triggers the synthesis of a substance known as cyclic guanosine monophosphate or cGMP.

The cGMP, in turn, signals the smooth muscle tissue lining the arteries that supply the penis to relax, and as they do, blood flow through those vessels increases sharply. Once the spongy erectile tissue of the penis has been filled with blood, erection is achieved. To ensure that the erection lasts until sexual activity is complete, the cGMP signals the veins that carry blood away from the penis to constrict, trapping blood in the penis and sustaining the erection.

One of the primary tasks of the PDE5 enzyme is to break down cGMP, which isn’t a serious problem in men with robust vascular systems because more cGMP is created to take its place. However, in men whose vascular systems are already compromised, the PDE5 can overwhelm the cGMP and sabotage the erection. PDE5 inhibitors hold the PDE5 enzyme at bay for four to 36 hours, allowing a window of opportunity for an erection to occur and sexual activity to be completed.

As previously noted, Viagra and the other PDE5 inhibitors are designed primarily to help men suffering from erectile dysfunction caused by insufficient blood flow to the penis, the single largest cause of ED. If your symptoms of ED are psychological in origin or caused by traumatic or congenital damage to your genitals, Viagra might be of little help.

Staxyn
Staxynbyedquestions

How long does it take for Staxyn to become effective?

Most men find that Staxyn becomes effective in about 15 minutes. That’s faster than the action of traditional Levitra, Viagra, and Cialis. Because it dissolves under the tongue, Staxyn can enter the bloodstream faster than a regular tablet. Still, however, doctors advise taking Staxyn one-half to one hour before sexual activity.

How long do the effects of Staxyn last?

A single dose of Staxyn is designed to last around six hours. However, if you take Staxyn and end up with an erection that lasts longer than four hours, it’s a medical emergency and you need to seek treatment immediately, or you risk permanent damage.

Staxyn can still be effective six or more hours after it’s taken.

Cialis
Cialisbyedquestions

What is the Link Between Cialis and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

A miniscule fraction of Cialis users reported vision loss. It was generally attributable to other causes, however.

In addition to the relatively minor eye problems of things appearing blue tinted, blurred vision, and difficulty distinguishing between green and blue, there have been a small number of reports of sudden vision loss. In these rare cases, a condition called non-arteritic anterior ischemic optic neuropathy (NAION) has been diagnosed. A total of 43 cases of NAION have been reported among users of erectile dysfunction drugs in the PDE-5 inhibitor class.

More specifically 38 Viagra users have reported it, as have four Cialis users and one Levitra user. This is a tiny number of people compared to the tens of millions of men who have safely taken these drugs over the past decade-plus.

What is the likeliest explanation for the problems?

The problem with attributing NAION to erectile dysfunction drugs like Cialis is that there’s no evidence that it was the drug that caused the vision problem. This form of blindness is among the most common causes of sudden loss of vision in older Americans. An estimated 1,000 to 6,000 cases are reported each year. Older Americans are not only the most likely to experience NAION, they’re the most likely to take drugs like Cialis, Viagra, and Levitra.

Complicating matters further, two of the main conditions that lead to NAION are diabetes and heart disease, which is significant because diabetes and heart disease are two leading causes of erectile dysfunction. In other words, it’s hard to say whether these men would have experienced vision loss if they hadn’t been taking erectile dysfunction drugs.

Cialis
Cialisbyedquestions

What is the Link Between Cialis and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

A miniscule fraction of Cialis users reported vision loss. It was generally attributable to other causes, however.

In addition to the relatively minor eye problems of things appearing blue tinted, blurred vision, and difficulty distinguishing between green and blue, there have been a small number of reports of sudden vision loss. In these rare cases, a condition called non-arteritic anterior ischemic optic neuropathy (NAION) has been diagnosed. A total of 43 cases of NAION have been reported among users of erectile dysfunction drugs in the PDE-5 inhibitor class.

More specifically 38 Viagra users have reported it, as have four Cialis users and one Levitra user. This is a tiny number of people compared to the tens of millions of men who have safely taken these drugs over the past decade-plus.

What is the likeliest explanation for the problems?

The problem with attributing NAION to erectile dysfunction drugs like Cialis is that there’s no evidence that it was the drug that caused the vision problem. This form of blindness is among the most common causes of sudden loss of vision in older Americans. An estimated 1,000 to 6,000 cases are reported each year. Older Americans are not only the most likely to experience NAION, they’re the most likely to take drugs like Cialis, Viagra, and Levitra.

Complicating matters further, two of the main conditions that lead to NAION are diabetes and heart disease, which is significant because diabetes and heart disease are two leading causes of erectile dysfunction. In other words, it’s hard to say whether these men would have experienced vision loss if they hadn’t been taking erectile dysfunction drugs.

Viagra
Viagrabyedquestions

26 Year Old Uncircumcised Having Problems Getting Erection Will Viagra Help

I’m a healthy 26-year-old man who’s uncircumcised. Lately, I’ve been having problems getting and keeping an erection. First, I’m curious to know whether getting circumcised would make it easier — or even more difficult — for me to get an erection. Second, I’m wondering if taking Viagra will help me regardless of whether I’m circumcised or not.

Several studies and systematic reviews of existing scientific literature have been undertaken in an effort to evaluate the effects if any, that circumcision has on male sexual function. A meta-analysis of data from 10 studies covering more than 18,500 men — 9,317 circumcised and 9,413 uncircumcised — produced no evidence that circumcision affects male sexual function in any way.

However, that review, published in the September 2013 issue of the “Asian Journal of Andrology,” acknowledged that the studies analyzed were of uneven quality and suggested that additional “well-designed and prospective studies” be conducted to shed additional light on the effects of circumcision on sexual function.

A more recent study, undertaken to test the hypothesis that male sexual function was somehow inferior after circumcision, failed to produce any evidence to support that theory. The second study, published in the July 2016 issue of the “Danish Medical Journal,” systematically reviewed data covering more than 3,677 men. However, one thing is clear. Circumcision has no effect whatsoever on the workings of Viagra.

The little blue pill might work for you or not, depending on a variety of factors, including the cause of your ED symptoms, but circumcision is not one of those factors.

Viagra
Viagrabyedquestions

26 Year Old Uncircumcised Having Problems Getting Erection Will Viagra Help

I’m a healthy 26-year-old man who’s uncircumcised. Lately, I’ve been having problems getting and keeping an erection. First, I’m curious to know whether getting circumcised would make it easier — or even more difficult — for me to get an erection. Second, I’m wondering if taking Viagra will help me regardless of whether I’m circumcised or not.

Several studies and systematic reviews of existing scientific literature have been undertaken in an effort to evaluate the effects if any, that circumcision has on male sexual function. A meta-analysis of data from 10 studies covering more than 18,500 men — 9,317 circumcised and 9,413 uncircumcised — produced no evidence that circumcision affects male sexual function in any way.

However, that review, published in the September 2013 issue of the “Asian Journal of Andrology,” acknowledged that the studies analyzed were of uneven quality and suggested that additional “well-designed and prospective studies” be conducted to shed additional light on the effects of circumcision on sexual function.

A more recent study, undertaken to test the hypothesis that male sexual function was somehow inferior after circumcision, failed to produce any evidence to support that theory. The second study, published in the July 2016 issue of the “Danish Medical Journal,” systematically reviewed data covering more than 3,677 men. However, one thing is clear. Circumcision has no effect whatsoever on the workings of Viagra.

The little blue pill might work for you or not, depending on a variety of factors, including the cause of your ED symptoms, but circumcision is not one of those factors.

Levitra
Levitrabyedquestions

Can I crush up regular Levitra and get the same effects as Staxyn?

No. Crushing up ordinary tablets in hopes of getting faster action can be seriously dangerous. With Levitra or other traditional ED medications, take them exactly as directed. The only exception to the “Don’t alter your pills” rule is using a pill splitter to cut 100 mg Viagra tablets in half if your doctor has prescribed 50 mg for you. Since the 50 mg and 100-mg doses usually cost the same, some doctors recommend buying 100 mg tablets and cutting them in half so you can essentially obtain 50 mg at half price.

Staxyn offers men yet another option for addressing erectile dysfunction effectively. It is safe for most men and offers added convenience since it doesn’t have to be taken with water. Men who get good results from taking Levitra generally find Staxyn to be a convenient alternative that works quickly and performs as expected.

Choosing the right medication to treat your erectile dysfunction requires weighing a number of factors. Drugs in the PDE-5 drug class work similarly, but their formulations differ somewhat. That means if one of them, for whatever reason doesn’t work well, or causes you to experience side effects, it’s still worthwhile to try the others. Sometimes it takes the right combination of personal physiology and drug formulation to get optimum results. However, if you didn’t get good results with Levitra, it’s unlikely you would get good results with Staxyn since they contain the same active ingredient.

However, you choose to address erectile dysfunction, picking the right treatment begins with a conversation with a physician. The products you can buy online from outlets that claim you don’t need a prescription are knock-offs, and there’s no way of telling what’s in them. At best you get something with no active ingredients. At worst, you could get something containing rat poison or drugs that have nothing to do with erectile dysfunction. Doctors are used to talking about erectile dysfunction, and you’re bringing up the subject will not faze them. Erectile dysfunction is a medical problem and in most cases, it has a medical solution.

Levitra
Levitrabyedquestions

Can I crush up regular Levitra and get the same effects as Staxyn?

No. Crushing up ordinary tablets in hopes of getting faster action can be seriously dangerous. With Levitra or other traditional ED medications, take them exactly as directed. The only exception to the “Don’t alter your pills” rule is using a pill splitter to cut 100 mg Viagra tablets in half if your doctor has prescribed 50 mg for you. Since the 50 mg and 100-mg doses usually cost the same, some doctors recommend buying 100 mg tablets and cutting them in half so you can essentially obtain 50 mg at half price.

Staxyn offers men yet another option for addressing erectile dysfunction effectively. It is safe for most men and offers added convenience since it doesn’t have to be taken with water. Men who get good results from taking Levitra generally find Staxyn to be a convenient alternative that works quickly and performs as expected.

Choosing the right medication to treat your erectile dysfunction requires weighing a number of factors. Drugs in the PDE-5 drug class work similarly, but their formulations differ somewhat. That means if one of them, for whatever reason doesn’t work well, or causes you to experience side effects, it’s still worthwhile to try the others. Sometimes it takes the right combination of personal physiology and drug formulation to get optimum results. However, if you didn’t get good results with Levitra, it’s unlikely you would get good results with Staxyn since they contain the same active ingredient.

However, you choose to address erectile dysfunction, picking the right treatment begins with a conversation with a physician. The products you can buy online from outlets that claim you don’t need a prescription are knock-offs, and there’s no way of telling what’s in them. At best you get something with no active ingredients. At worst, you could get something containing rat poison or drugs that have nothing to do with erectile dysfunction. Doctors are used to talking about erectile dysfunction, and you’re bringing up the subject will not faze them. Erectile dysfunction is a medical problem and in most cases, it has a medical solution.

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