The beautiful thing about sex is that you never know when the mood is going to strike. You and your partner might set out for a night of lovemaking, or you might be bundle up in your pajamas watching Netflix and suddenly the feeling strikes. But no matter when the mood hits, if you’re a man with erectile dysfunction, you have to be ready. But as you can find yourself hopping between the sheets at seemingly any moment, you won’t always have the luxury of having the perfect situation for erectile dysfunction drugs to work swiftly. We all know that ED drugs such as Viagra work best when taken on an empty stomach, but what about men that need to knock boots after finishing a meal? Can Viagra even work when taken on a full stomach?

It’s not like a full stomach will negate the effects of Viagra. No matter how big your last meal was, Viagra will still work; but depending on how full you are, how quickly it will begin to work can vary wildly.

When Viagra is taken properly (i.e., empty stomach, no alcohol, etc.), it typically takes the little blue pill between 45 minutes to an hour to take effect. But when food is introduced to the mix, this timeline changes. As your stomach digests what’s in your stomach in the order it entered your stomach, Viagra will essentially have to wait in line to be digested and distributed throughout your body. When taken on a full stomach, the turnaround time for Viagra’s effects jumps to over an hour, and can even reach the two to three hour mark.

So if you’re looking to get down to business between the sheets, try to take Viagra on a relatively empty stomach. Otherwise, be prepared to play the waiting game.